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Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. R American Heart Association. Smoking Smoking can lower your HDL levels because a chemical in cigarette smoke called acrolein appears to change the way HDL works in the body.

Insulin resistance If you have too much fat stored in your body, particularly around your waistline, the hormone insulin is less able to control your blood sugar. The LDL cholesterol also tend to be smaller and more harmful to the arteries. Losing weight can help raise your HDL cholesterol. Genetic conditions Rarely, very low HDL cholesterol can be caused by your genes. Tangier disease. This is a very rare condition which causes no or very low levels of HDL cholesterol.

LDL cholesterol levels are also usually low. A fault in a gene affects the transport of cholesterol from your cells to your HDL lipoproteins. ApoA1 deficiency. Get Email Updates.

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